Biological Theories of Depression
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Several lines of evidence suggest that the classic neurotransmitters, norepinephrine, acetylcholine, and serotonin, play important roles in the pathogenesis of depressive illness. Other biochemical compounds and peptides may also be involved in the etiology of some forms of mood disorders. No one theory will completely explain the biological bases for depression because depression is really a syndrome, rather than a specific unitary disease state. (41 pp.)