Our biological rhythms make each of us a microcosm of the geophysical world. This chapter will review the evidence that links affective illness to disturbances in the circadian system. It will also describe a circadian theory of depression and mania and possible circadian mechanisms of drugs and procedures that are used in their treatment. (74 pp.)
Download Author: Goodwin, Frederick K.
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The Psychobiology of Mania
This chapter will review studies of mania and of the bipolar patient group, concentrating in particular on investigations of biogenic amines, drug responses, sleep, other biologic changes, and some quantitatively assessed behavioral phenomena in manic individuals. (83 pp.)
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